Rapid identification of molecular subtyping of breast cancer cell lines using a multi-channel sensor array

Abstract

In this paper, we present a multi-channel sensor array composed of three fluorescent probes that can be used to identify and differentiate breast cancer molecular subtypes, including luminal A, luminal B, HER2-enriched and triple-negative. The multi-channel sensor array allows the three probes to mix and interact with each cell sample in one well simultaneously, resulting in high efficiency, lower sample costs, and 100% accuracy in cell molecular subtype differentiation.