Issue 1, 2011
From the journal:

RSC Advances

A novel application of porphyrinnanoparticles as an effective fluorescent assay platform for nucleic acid detection†

Junfeng Zhai,‡a   Hailong Li‡ab  and  Xuping Sun*a  

* Corresponding authors

a State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 Jilin, China
E-mail: sunxp@ciac.jl.cn
Fax: (+86) 431-85262065
Tel: (+86) 431-85262065

b Graduate School of the Chinese Academy of Sciences, Beijing 100039, China

Abstract

The present communication demonstrates the preparation of 2,3,7,8,12,13,17,18-octaethyl-21H,23H-porphine iron(III) chloride nanoparticles (FePNPs) by reprecipitation method. In a further effort, the potential application of FePNPs was exploited as an effective fluorescent assay platform for nucleic acid detection. This assay system exhibits high sensitivity and selectivity down to a single-base mismatch.

Graphical abstract: A novel application of porphyrin nanoparticles as an effective fluorescent assay platform for nucleic acid detection

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Article information

DOI
https://doi.org/10.1039/C1RA00026H
Article type
Communication
Submitted
12 Apr. 2011
Accepted
09 Maijs 2011
First published
21 Jūl. 2011

RSC Adv., 2011,1, 36-39

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A novel application of porphyrin nanoparticles as an effective fluorescent assay platform for nucleic acid detection

J. Zhai, H. Li and X. Sun, RSC Adv., 2011, 1, 36 DOI: 10.1039/C1RA00026H

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