Fluorinated smart micelles as enzyme-responsive probes for 19F-magnetic resonance

Abstract

Labeling of smart PEG–dendron hybrids with fluorinated groups transformed their assemblies into enzyme-responsive micellar probes for ¹⁹F-magnetic resonance (MR). Two distinct labeling approaches were used to study the ability of these smart hybrids to be turned OFF at the assembled micellar state and to turn ON their ¹⁹F-MR signal upon enzymatic activation.