Mesoporous silica nanobeans dual-functionalized with AIEgens and leaning pillar[6]arene-based supramolecular switches for imaging and stimuli-responsive drug release

Xiangshuai Li; Junyou Han; Jianchun Qin; Ming Sun; Jiarui Wu; Liancheng Lei; Jing Li; Lei Fang; Ying-Wei Yang

doi:10.1039/C9CC07115F

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Mesoporous silica nanobeans dual-functionalized with AIEgens and leaning pillar[6]arene-based supramolecular switches for imaging and stimuli-responsive drug release†

Xiangshuai Li,‡^ab Junyou Han,‡^b Jianchun Qin,‡^b Ming Sun,^c Jiarui Wu,

^a Liancheng Lei,^c Jing Li,^a Lei Fang

*^d and Ying-Wei Yang

*^a

Author affiliations

* Corresponding authors

^a College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China
E-mail: ywyang@jlu.edu.cn

^b College of Plant Science, Jilin University, 5333 Xi’an Street, Changchun 130062, China

^c College of Veterinary Medicine, Jilin University, 5333 Xi’an Street, Changchun 130062, China

^d Department of Chemistry, Texas A&M University 3255 TAMU, College Station, TX 77843-3255, USA
E-mail: fang@chem.tamu.edu

Abstract

A bean-shaped and dual-functionalized organic–inorganic hybrid supramolecular system with a GSH-dependent turn-on fluorescence enhancement property and stimuli-responsive drug delivery function endowed with leaning towerarene-based switches has been constructed for simultaneous tumor inhibition and imaging.

This article is part of the themed collection: Cucurbiturils and related cavitands

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Article information

DOI: https://doi.org/10.1039/C9CC07115F
Article type: Communication
Submitted: 12 Sept. 2019
Accepted: 09 Okt. 2019
First published: 09 Okt. 2019

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Chem. Commun., 2019,55, 14099-14102

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Mesoporous silica nanobeans dual-functionalized with AIEgens and leaning pillar[6]arene-based supramolecular switches for imaging and stimuli-responsive drug release

X. Li, J. Han, J. Qin, M. Sun, J. Wu, L. Lei, J. Li, L. Fang and Y. Yang, Chem. Commun., 2019, 55, 14099 DOI: 10.1039/C9CC07115F

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Chemical Communications

Mesoporous silica nanobeans dual-functionalized with AIEgens and leaning pillar[6]arene-based supramolecular switches for imaging and stimuli-responsive drug release†

Abstract

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Mesoporous silica nanobeans dual-functionalized with AIEgens and leaning pillar[6]arene-based supramolecular switches for imaging and stimuli-responsive drug release

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