Coumarin functionalized molecular scaffolds for the effectual detection of hazardous fluoride and cyanide

Abstract

Fluoride and cyanide contamination in drinking water imposes detrimental impacts on human health above their permissible limits. Hence, the quantitative detection of these colourless water-soluble toxins has attracted attention. Even though a plethora of chemosensors have been reported so far for the detection of fluoride and cyanide from various matrices, still their applicability is limited to a few examples. Nevertheless, recent advances in the syntheses of coumarin derivatives have shown significant impact on fluoride and cyanide detection. Therefore, this present review provides a brief overview of the application of coumarin-coupled molecular scaffolds towards the detection of perilous fluoride and cyanide along with their sensing mechanisms in order to develop more innovative, simple, sensitive, real-time responsive and cost-effective coumarin-based supramolecular chemosensors to promote next generation approaches towards the ultra-trace quantitative detection of these toxic anions.