Cancer diagnostics
Guest editors Bin Liu and James F. Rusling introduce this Journal of Materials Chemistry B themed issue on cancer diagnostics.
Research progresses on the functional polypeptides in the detection and imaging of breast cancer
Polypeptides as functional groups continue to garner significant interest in the detection and imaging of breast cancer, working as recognition elements, signal sources, building blocks and therapeutic reagents, etc.
A rapid and highly sensitive strain-effect graphene-based bio-sensor for the detection of stroke and cancer bio-markers
A bio-sensor for the detection of cancer biomarkers utilizing the adsorption properties of ruthenium carbonyl on monolayer graphene.
A redox-responsive folate–fluorophore conjugate as a new target-cell-specific imaging probe
Here, we have developed a redox-responsive folate–fluorophore conjugate with a disulfide linker for the target-specific activatable fluorescence imaging of cancers.
Metalla-aromatic loaded magnetic nanoparticles for MRI/photoacoustic imaging-guided cancer phototherapy
In this study, metalla-aromatic agents and a cluster of superparamagnetic iron oxide nanoparticles were loaded inside a micellar carrier and used for MRI/PA imaging-guided PTT/PDT synergistic cancer therapy.
Organic nanoparticles with ultrahigh quantum yield and aggregation-induced emission characteristics for cellular imaging and real-time two-photon lung vasculature imaging
Organic nanoparticles with a high quantum yield of 90% and aggregation-induced emission characteristics were prepared for cellular imaging and real-time two-photon vasculature imaging of the lungs.
An efficient synergistic cancer therapy by integrating cell cycle inhibitor and photosensitizer into polydopamine nanoparticles
A novel polydopamine (PDA) based nanocomposite loaded with cell cycle inhibitor (NOC) and photosensitizer (ZnPc12+) was developed for efficient synergistic cancer therapy.
Imaging and evaluation of sulfane sulfur in acute brain ischemia using a mitochondria-targeted near-infrared fluorescent probe
Imaging and evaluation of sulfane sulfur in acute brain ischemia using a mitochondria-targeted near-infrared fluorescent probe
A novel core–shell structured upconversion nanorod as a multimodal bioimaging and photothermal ablation agent for cancer theranostics
A multifunctional core–shell nanocomposite based on noble metal plasmons coated with upconversion material has emerged as a promising cancer theranostics nanoplatform.
Mannan-based conjugates as a multimodal imaging platform for lymph nodes
We show that mannan-based conjugates possess exceptional features for multimodal imaging because of their biocompatibility, biodegradability and self-targeting properties.
In vivo tumor active cancer targeting and CT-fluorescence dual-modal imaging with nanoprobe based on gold nanorods and InP/ZnS quantum dots
Gold nanorod, InP/ZnS QD and c(RGDfC) based multifunctional nanoprobe for dual-modal imaging of active targeting of tumors in vivo.
Enzyme-instructed self-assembly leads to the activation of optical properties for selective fluorescence detection and photodynamic ablation of cancer cells
An aggregation-induced emission luminogen (AIEgen)-based probe with both fluorescence and photoactivity activatable characteristics is developed for cancer theranostics.
A simple mitochondrial targeting AIEgen for image-guided two-photon excited photodynamic therapy
A simple AIE luminogen, IQ-TPA, with mitochondrial targeting was demonstrated for image-guided two-photon excited photodynamic therapy in cancer cells.
A sequential enzyme-activated and light-triggered pro-prodrug nanosystem for cancer detection and therapy
A sequential enzyme-activated and light-triggered pro-prodrug has been developed for cancer biomarker detection and on-demand therapy.
Near-infrared fluorescent probes for the detection of glutathione and their application in the fluorescence imaging of living cells and tumor-bearing mice
We present two new cyanine-based NIR fluorescent probes for imaging GSH in living cells and tumor-bearing mice.