Mengyang Zhang, Junqing He, Youbin Zheng, Guoyue Shi and Min Zhang
Analyst, 2022,147, 4413-4416
DOI:
10.1039/D2AN01393B,
Communication
Herein, we report a portable point-of-care testing (POCT) device based on an aptamer-engineered extended-gate field-effect transistor (EG-FET) for therapeutic monitoring of the drug methotrexate. This method was shown to be highly sensitive, efficient, and convenient to use, features contributing to its realizing a clinical detection of drugs in blood.