A tutorial review for research laboratories to support the vital path toward inherently sustainable and green synthetic chemistry

Abstract

For synthetic chemistry to become inherently sustainable and green in its design and implementation, each research group must reflect, (re)assess practices, (re)define goals, embed new concepts, commit to a new mindset, and implement necessary change. This is a complex challenge, requiring measurable actions as starting points and during the implementation phase. This tutorial review aims to provide insight and background context into this area, highlighting several starting points to be considered by synthetic chemistry research laboratories. It is designed for new researchers to review at the start of their journey and to inform existing researchers of key methodologies for application in their research. Metrics, sustainable research design and solvent considerations are discussed, along with background understanding on commitment to change. The review also presents practical aspects to be applied within a laboratory and its daily practices and operations, a key element of any synthetic chemistry research.