W. B. Struwe, J. L. Benesch, D. J. Harvey and K. Pagel
Analyst, 2015,140, 6799-6803
DOI:
10.1039/C5AN01092F,
Communication
We report collision cross sections (CCS) of high-mannose N-glycans as [M + Na]+, [M + K]+, [M + H]+, [M + Cl]−, [M + H2PO4]− and [M − H]− ions, measured by drift tube (DT) ion mobility-mass spectrometry (IM-MS) in helium and nitrogen gases. Further analysis using traveling wave (TW) IM-MS reveal the existence of distinct conformers exclusive to [M − H]− ions.