Ayaat Mohamed Mahmoud, Alexander Rajakanthan and Kristian Kempe
Polym. Chem., 2018,9, 1562-1566
DOI:
10.1039/C7PY01912B,
Communication
The SZWIP of 2-oxazolines enables the one-pot synthesis of N-acylated poly(amino ester) based macromonomers with tuneable hydrophobicity. Their redox-initiated RAFT (co-)polymerisation yields hydrophobic homo- or amphiphilic block comb polymers with pendant carboxy groups, which can be self-assembled into nano-sized pH-responsive aggregates. The availability for further functionalisations in combination with their non-toxicity highlights their future potential for biomedical applications.