Recent advances in Cu-catalyzed transformations of internal alkynes to alkenes and heterocycles

Numerous metal-catalyzed reactions involving internal alkynes and aimed towards synthetically and pharmacologically important alkenes and heterocycles have appeared in the literature. Among these, Cu-catalyzed reactions have a special place, which has prompted the investigation and development of carbon–carbon and carbon–heteroatom bond-forming reactions. These reactions possess wide scope, and during the paths of these reactions, either stable or in situ intermediates are formed via the addition of Cu as a core catalyst or synergistic catalyst. In this review, we aim to report different contributions relating to Cu-catalyzed reactions of internal alkynes for the synthesis of different valuable alkenes and heterocycles which have appeared in the literature in the last decade. We anticipate that this appraisal will deliver basic insights for the further advancement of Cu-catalyzed reactions in organic chemistry.