C–H hetero-functionalization of arenes through palladacyclopentane-type intermediates

Recent years have witnessed palladium-catalyzed C–H activation emerging as a versatile strategy for the construction of valuable scaffolds. Palladacyclopentane-type intermediates, usually created by C–H activation from an aryl-Pd(II) precursor, provide opportunities for subsequent C–H hetero-functionalizations and have therefore received much attention in organic synthesis. In this review article, we summarise recent advances in the C–H hetero-functionalization of arenes through palladacyclopentane-type intermediates over the past decade.