Issue 13, 2016

Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

Abstract

The signal enhancement properties of QCM sensors based on dynamic, biotinylated poly(acrylic acid) brushes has been studied in interaction studies with an anti-biotin Fab fragment. The poly(acrylic acid) sensors showed a dramatic increase in signal response with more than ten times higher signal than the carboxyl-terminated self-assembled monolayer surface.

Graphical abstract: Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

Supplementary files

Article information

Article type
Communication
Submitted
29 Cig 2016
Accepted
11 Cax 2016
First published
12 Cax 2016
This article is Open Access
Creative Commons BY-NC license

Analyst, 2016,141, 3993-3996

Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

G. Dunér, H. Anderson, Z. Pei, B. Ingemarsson, T. Aastrup and O. Ramström, Analyst, 2016, 141, 3993 DOI: 10.1039/C6AN00735J

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