Issue 62, 2021

Micelle enabled C(sp2)–C(sp3) cross-electrophile coupling in water via synergistic nickel and copper catalysis

Abstract

A robust and sustainable C(sp2)–C(sp3) cross-electrophile coupling was developed via nickel/copper synergistic catalysis under micellar conditions. This protocol provided a general method to access alkylated arenes with good to excellent yields on a very large scale.

Graphical abstract: Micelle enabled C(sp2)–C(sp3) cross-electrophile coupling in water via synergistic nickel and copper catalysis

Supplementary files

Article information

Article type
Communication
Submitted
01 iyn 2021
Accepted
30 iyn 2021
First published
30 iyn 2021

Chem. Commun., 2021,57, 7629-7632

Micelle enabled C(sp2)–C(sp3) cross-electrophile coupling in water via synergistic nickel and copper catalysis

N. Ye, B. Wu, K. Zhao, X. Ge, Y. Zheng, X. Shen, L. Shi, M. Cortes-Clerget, M. L. Regnier, M. Parmentier and F. Gallou, Chem. Commun., 2021, 57, 7629 DOI: 10.1039/D1CC02885E

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