Issue 76, 2016
From the journal:

Chemical Communications

Fluorogenic bidirectional displacement probe-based real-time isothermal DNA amplification and specific visual detection of products†

Xiong Ding,ab   Guoping Wang,ab   Jingjing Sun,ab   Tao Zhanga  and  Ying Mu*a  

* Corresponding authors

a Research Center for Analytical Instrumentation, Institute of Cyber-Systems and Control, State Key Laboratory of Industrial Control Technology, Zhejiang University, Hangzhou, P. R. China
E-mail: muying@zju.edu.cn

b Institute of Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou, P. R. China

Abstract

A unique fluorogenic nucleic acid probe has been devised, called the fluorogenic bidirectional displacement probe, which can serve as both the primer and the signal indicator of amplification products for the development of the real-time isothermal DNA amplification and its visual detection of products with high sensitivity and specificity.

Graphical abstract: Fluorogenic bidirectional displacement probe-based real-time isothermal DNA amplification and specific visual detection of products

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Article information

DOI
https://doi.org/10.1039/C6CC05158H
Article type
Communication
Submitted
21 Jun 2016
Accepted
17 Aug 2016
First published
24 Aug 2016

Chem. Commun., 2016,52, 11438-11441

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Fluorogenic bidirectional displacement probe-based real-time isothermal DNA amplification and specific visual detection of products

X. Ding, G. Wang, J. Sun, T. Zhang and Y. Mu, Chem. Commun., 2016, 52, 11438 DOI: 10.1039/C6CC05158H

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