Issue 18, 1974

Regioselective base-catalysed rearrangement of steroidal αβ-unsaturated epoxides

Abstract

Rearrangement of 5,10-epoxy-Δ9(11)-steroids in the presence of potassium t-butoxide or lithium dialkylamides occurs by proton abstraction at C-4 or C-12 depending on the nature of the base and the configuration of the epoxide.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1974, 763-764

Regioselective base-catalysed rearrangement of steroidal αβ-unsaturated epoxides

G. Teutsch and R. Bucourt, J. Chem. Soc., Chem. Commun., 1974, 763 DOI: 10.1039/C39740000763

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