Concise syntheses of 4-(arylcarbonylmethyl)-azetidin-2-ones and related systems
Abstract
On catalysis by trimethylsilyl trifluoromethane-sulphonate, 4-acetoxy-1-trimethylsilylazetidin-2-one reacted with the enol silanes [R1CHC(OSiMe3)R2] to give the β-lactams [[graphic omitted]HCH(R1)COR2] in excellent yields (71 to 95%).