Studies on the reactivity of 2-furylhydroxymethylphosphonates: synthesis of 1-oxo-4-hydroxycyclopent-2-en-5-ylphosphonates
Abstract
Starting from 2-furylhydroxymethylphosphonates (1), a facile and direct preparation of the previously unknown phosphonate-containing cyclopentenones (5), potential new synthons in the elaboration of rethrolone- and prostaglandin-related compounds, is described.