Novel conversion of E stereoselectivity to Z stereoselectivity in trifluoromethylated α,β-unsaturated esters and nitriles by way of O-methylation of an ylide anion
Abstract
A stereocontrolled synthesis of (Z)-trifluoromethylated α,β-unsaturated esters and nitriles by way of O-methylation of an ylide anion is described.