Formation of 1,11-bis(pendant donor)-cyclam derivatives via the formamidinium salt (cyclam = 1,4,8,11-tetraazacyclotetradecane)
Abstract
When reacted in chloroform, the dimethyl acetal of dmf and cyclam (1,4,8,11-tetraazacyclotetradecane) forms a stable formamidinium salt which can be used as an intermediate for very simple formation of 1,11-bis(pendant donor)-cyclam derivatives.