A new strategy towards the total synthesis of phenanthridone alkaloids: synthesis of (+)-2,7-dideoxypancratistatin as a model study
Abstract
A new strategy towards the synthesis of phenanthridone alkaloids has been reported through the synthesis of (+)-2,7-dideoxypancratistatin from D-(−)-quinic acid employing PET initiated carbocyclization of an electron rich aromatics by silylenol ether as a key step.