Issue 8, 2003

A new dark quencher for use in genetic analysis

Abstract

A novel, long-wavelength, non-fluorescent quencher (LQ), based on 1,4-diaminoanthraquinone, has been incorporated at the 3′ and 5′-termini of oligonucleotides. The quencher has been used in Molecular beacons, efficiently quenching the long wavelength fluorophore, Cy5.

Graphical abstract: A new dark quencher for use in genetic analysis

Article information

Article type
Communication
Submitted
23 Jan 2003
Accepted
06 Mar 2003
First published
18 Mar 2003

Chem. Commun., 2003, 970-971

A new dark quencher for use in genetic analysis

J. P. May, L. J. Brown, I. Rudloff and T. Brown, Chem. Commun., 2003, 970 DOI: 10.1039/B300934C

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