Transamination chemistry of sodium TMP-zincate: synthesis and crystal structure of a chiral amidozincate

David R. Armstrong; William Clegg; Sophie H. Dale; Joaquín García-Álvarez; Ross W. Harrington; Eva Hevia; Gordon W. Honeyman; Alan R. Kennedy; Robert E. Mulvey; Charles T. O'Hara

doi:10.1039/B713987J

Transamination chemistry of sodium TMP-zincate: synthesis and crystal structure of a chiral amidozincate†

David R. Armstrong,^a William Clegg,^b Sophie H. Dale,^b Joaquín García-Álvarez,^a Ross W. Harrington,^b Eva Hevia,*^a Gordon W. Honeyman,^a Alan R. Kennedy,^a Robert E. Mulvey*^a and Charles T. O'Hara^a

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^a WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow, UK
E-mail: eva.hevia@strath.ac.uk, r.e.mulvey@strath.ac.uk

^b School of Natural Sciences (Chemistry), Newcastle University, Newcastle upon Tyne, UK

Abstract

In a new type of reactivity for sodium TMP-zincate [(TMEDA)NaZn(^tBu)₂(TMP)] (1), transamination reactions with the amines diisopropylamine, DA(H), hexamethyldisilazane, HMDS(H) and chiral (R)-N-benzyl-α-methylbenzylamine have produced new sodium amido-di-tert-butyl zincates (all structurally characterised) with concomitant loss of TMP(H).

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Transamination chemistry of sodium TMP-zincate: synthesis and crystal structure of a chiral amidozincate†

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Transamination chemistry of sodium TMP-zincate: synthesis and crystal structure of a chiral amidozincate

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