Issue 41, 2008
From the journal:

Chemical Communications

Metal free thiol–maleimide ‘Click’ reaction as a mild functionalisation strategy for degradable polymers†

Ryan J. Pounder,a   Matthew J. Stanford,a   Paul Brooks,a   Stephen P. Richardsa  and  Andrew P. Dove*a  

* Corresponding authors

a Department of Chemistry, University of Warwick, Coventry, UK
E-mail: a.p.dove@warwick.ac.uk
Tel: +44 (0)24 7652 4107

Abstract

The stoichiometric reaction between thiols and maleimide-functional poly(ester)s is demonstrated to be a quantitative, tolerant, mild and efficient method for polymer modification.

Graphical abstract: Metal free thiol–maleimide ‘Click’ reaction as a mild functionalisation strategy for degradable polymers

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Article information

DOI
https://doi.org/10.1039/B809167F
Article type
Communication
Submitted
30 May 2008
Accepted
22 Jul 2008
First published
29 Sep 2008

Chem. Commun., 2008, 5158-5160

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Metal free thiol–maleimide ‘Click’ reaction as a mild functionalisation strategy for degradable polymers

R. J. Pounder, M. J. Stanford, P. Brooks, S. P. Richards and A. P. Dove, Chem. Commun., 2008, 5158 DOI: 10.1039/B809167F

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