Issue 42, 2009
From the journal:

Chemical Communications

Label-free aptamer-based sensor using abasic site-containing DNA and a nucleobase-specific fluorescent ligand†

Zhiai Xu,a   Kotaro Morita,a   Yusuke Sato,a   Qing Dai,a   Seiichi Nishizawaa  and  Norio Teramae*a  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan
E-mail: teramae@mail.tains.tohoku.ac.jp
Fax: +81-22-795-6552
Tel: +81-22-795-6549

Abstract

A label-free adenosine sensor with emissive response is designed based on an AP site-containing aptamer/DNA duplex and a small fluorescent molecule 2-amino-5,6,7-trimethyl-1,8-naphthyridine (ATMND).

Graphical abstract: Label-free aptamer-based sensor using abasic site-containing DNA and a nucleobase-specific fluorescent ligand

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Article information

DOI
https://doi.org/10.1039/B908345F
Article type
Communication
Submitted
27 Apr 2009
Accepted
10 Sep 2009
First published
30 Sep 2009

Chem. Commun., 2009, 6445-6447

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Label-free aptamer-based sensor using abasic site-containing DNA and a nucleobase-specific fluorescent ligand

Z. Xu, K. Morita, Y. Sato, Q. Dai, S. Nishizawa and N. Teramae, Chem. Commun., 2009, 6445 DOI: 10.1039/B908345F

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