Issue 6, 2009
From the journal:

Organic & Biomolecular Chemistry

Targeting ketonedrugs towards transport by the intestinal peptide transporter, PepT1†

David Foley,a   Patrick Bailey,*b   Myrtani Pieric  and  David Meredithc  

* Corresponding authors

a School of Chemistry, University of Manchester, Manchester, UK
E-mail: david.foley@postgrad.manchester.ac.uk

b Faculty of Natural Sciences, Keele University, Keele, Staffordshire, UK
E-mail: p.bailey@natsci.keele.ac.uk
Fax: +44 (0)1782 584593
Tel: +44 (0)1782 584583

c School of Life Sciences, Oxford Brookes University, Headington, Oxford, UK

Abstract

Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro.

Graphical abstract: Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1

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Article information

DOI
https://doi.org/10.1039/B818606E
Article type
Communication
Submitted
21 Oct 2008
Accepted
05 Jan 2009
First published
21 Jan 2009
This article is Open Access

Org. Biomol. Chem., 2009,7, 1064-1067

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Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1

D. Foley, P. Bailey, M. Pieri and D. Meredith, Org. Biomol. Chem., 2009, 7, 1064 DOI: 10.1039/B818606E

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