Issue 3, 2010
From the journal:

Chemical Communications

Pd-catalyzed cascade Heck–Saegusa: direct synthesis of enals from aryl iodides and allyl alcohol†

Jie Liu,a   Jin Zhu,a   Hualiang Jiang,ac   Wei Wang*abc  and  Jian Li*a  

* Corresponding authors

a School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China
E-mail: jianli@ecust.edu.cn
Fax: (+86) 21-64252584
Tel: (+86) 21-64252584

b Department of Chemistry and Chemical Biology, University of New Mexico, MSC03 2060, Albuquerque, USA
E-mail: wwang@unm.edu
Fax: (+1) 505-277-2609

c Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China

Abstract

A new efficient Pd-catalyzed cascade Heck–Saegusa protocol for the synthesis of synthetically useful α,β-unsaturated aldehydes in high yields from readily available aryl iodides and allyl alcohol has been developed.

Graphical abstract: Pd-catalyzed cascade Heck–Saegusa: direct synthesis of enals from aryl iodides and allyl alcohol

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Article information

DOI
https://doi.org/10.1039/B922351G
Article type
Communication
Submitted
26 Oct 2009
Accepted
23 Nov 2009
First published
01 Dec 2009

Chem. Commun., 2010,46, 415-417

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Pd-catalyzed cascade Heck–Saegusa: direct synthesis of enals from aryl iodides and allyl alcohol

J. Liu, J. Zhu, H. Jiang, W. Wang and J. Li, Chem. Commun., 2010, 46, 415 DOI: 10.1039/B922351G

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