A novel profluorescent probe for detecting oxidative stress induced by metal and H2O2 in living cells

Abstract

A profluorescent probe that has no fluorescent response to H₂O₂, iron or copper ions but can be readily activated in the presence of both H₂O₂ and Fe (or Cu) ion has been developed; the probe is capable of detecting oxidative stress promoted by Fe (or Cu) and H₂O₂ (i.e. the Fenton reaction conditions) in living cells.