Issue 6, 2011
From the journal:

Chemical Communications

Synthesis of histone H3 proteins by a thioacid capture ligation strategy†

Xiaohong Zhang,a   Fupeng Lia  and  Chuan-Fa Liu*a  

* Corresponding authors

a Division of Chemical Biology and Biotechnology, School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 63755, Singapore
E-mail: cfliu@ntu.edu.sg
Fax: +65 6791-3856

Abstract

The first application of thioacid capture ligation in protein synthesis is described. Two histone H3 proteins were synthesized in which a 30 min ligation reaction gave the protein products in good yields.

Graphical abstract: Synthesis of histone H3 proteins by a thioacid capture ligation strategy

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Article information

DOI
https://doi.org/10.1039/C0CC03666H
Article type
Communication
Submitted
04 Sep 2010
Accepted
03 Nov 2010
First published
29 Nov 2010

Chem. Commun., 2011,47, 1746-1748

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Synthesis of histone H3 proteins by a thioacid capture ligation strategy

X. Zhang, F. Li and C. Liu, Chem. Commun., 2011, 47, 1746 DOI: 10.1039/C0CC03666H

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