Issue 6, 2011
From the journal:

Chemical Communications

Label-free electrochemical impedance sensing of DNA hybridization based on functionalized graphene sheets†

Yuwei Hu,ab   Fenghua Li,a   Xiaoxue Bai,b   Dan Li,b   Shucheng Hua,*b   Kaikai Wanga  and  Li Niu*ab  

* Corresponding authors

a Engineering Laboratory for Modern Analytical Techniques, c/o State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China
E-mail: lniu@ciac.jl.cn
Fax: +86 431-85262800
Tel: +86 431-85262425

b College of Chemistry and Norman Bethune College of Medicine, Jilin University, Changchun 130021, PR China
Tel: +86431-85612222

Abstract

Negative-charge change and conformation transition upon DNA immobilization and hybridization on functionalized graphene sheets were monitored by the EIS technique and adopted as the signal for label-free electrochemical DNA hybridization detection.

Graphical abstract: Label-free electrochemical impedance sensing of DNA hybridization based on functionalized graphene sheets

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Article information

DOI
https://doi.org/10.1039/C0CC04514D
Article type
Communication
Submitted
20 Oct 2010
Accepted
15 Nov 2010
First published
01 Dec 2010

Chem. Commun., 2011,47, 1743-1745

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Label-free electrochemical impedance sensing of DNA hybridization based on functionalized graphene sheets

Y. Hu, F. Li, X. Bai, D. Li, S. Hua, K. Wang and L. Niu, Chem. Commun., 2011, 47, 1743 DOI: 10.1039/C0CC04514D

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