Issue 14, 2011
From the journal:

Chemical Communications

High-relaxivity MRI contrast agents prepared from miniemulsion polymerization using gadolinium(iii)-based metallosurfactants†

Pei Gong,a   Zhengyan Chen,a   Yingying Chen,a   Wei Wang,a   Xiaosong Wang*ab  and  Aiguo Hu*a  

* Corresponding authors

a Key Lab for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Rd, Shanghai, China
E-mail: hagmhsn@ecust.edu.cn

b Department of Colour Science, School of Chemistry, University of Leeds, Leeds, UK
E-mail: X.S.Wang@leeds.ac.uk

Abstract

Miniemulsion polymerization with amphiphilic gadolinium(III) complexes as metallosurfactants was explored as a new technique for the synthesis of high relaxivity MRI contrast agents. Well-defined metallo-colloids with up to 240% enhancement in relaxivity over their small molecular counterparts were obtained.

Graphical abstract: High-relaxivity MRI contrast agents prepared from miniemulsion polymerization using gadolinium(iii)-based metallosurfactants

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Article information

DOI
https://doi.org/10.1039/C0CC05746K
Article type
Communication
Submitted
23 Dec 2010
Accepted
10 Feb 2011
First published
25 Feb 2011

Chem. Commun., 2011,47, 4240-4242

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High-relaxivity MRI contrast agents prepared from miniemulsion polymerization using gadolinium(III)-based metallosurfactants

P. Gong, Z. Chen, Y. Chen, W. Wang, X. Wang and A. Hu, Chem. Commun., 2011, 47, 4240 DOI: 10.1039/C0CC05746K

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