Issue 15, 2011

A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

Abstract

A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.

Graphical abstract: A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

Supplementary files

Article information

Article type
Communication
Submitted
30 Jan 2011
Accepted
28 Feb 2011
First published
14 Mar 2011

Chem. Commun., 2011,47, 4373-4375

A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

X. Chen, K. Lee, E. Ha, K. M. Lee, Y. Y. Seo, H. K. Choi, H. N. Kim, M. J. Kim, C. Cho, S. Y. Lee, W. Lee and J. Yoon, Chem. Commun., 2011, 47, 4373 DOI: 10.1039/C1CC10589B

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