Issue 26, 2011
From the journal:

Chemical Communications

Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells†

David G. Smith,a   Ga-lai Law,a   Benjamin S. Murray,a   Robert Pal,a   David Parker*a  and  Ka-Leung Wongab  

* Corresponding authors

a Department of Chemistry, Durham University, South Road, Durham, UK
E-mail: david.parker@dur.ac.uk

b Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong

Abstract

Image and spectral intensity from bicarbonate-selective europium(III) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO2, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide.

Graphical abstract: Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

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Article information

DOI
https://doi.org/10.1039/C1CC11853F
Article type
Communication
Submitted
01 Apr 2011
Accepted
04 May 2011
First published
02 Jun 2011

Chem. Commun., 2011,47, 7347-7349

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Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

D. G. Smith, G. Law, B. S. Murray, R. Pal, D. Parker and K. Wong, Chem. Commun., 2011, 47, 7347 DOI: 10.1039/C1CC11853F

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