Issue 37, 2011
From the journal:

Chemical Communications

Diffusion of small molecules inside a peptide hydrogel†

Yue Feng,a   Manfai Lee,a   Marc Tarabanb  and  Y. Bruce Yu*ab  

* Corresponding authors

a Department of Pharmaceutical Sciences, University of Maryland, Baltimore, USA
E-mail: byu@rx.umaryland.edu
Fax: +1 4017065017
Tel: +1 4017067514

b Fischell Department of Bioengineering, University of Maryland, College Park, USA

Abstract

A set of four phenylalanine analogues experiences diffusion retardation when transferred from phosphate-buffered saline into a peptide hydrogel of the same pH and ionic strength. The extent of retardation increases linearly with logPoct, their lipophilicity.

Graphical abstract: Diffusion of small molecules inside a peptide hydrogel

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Article information

DOI
https://doi.org/10.1039/C1CC13943F
Article type
Communication
Submitted
01 Jul 2011
Accepted
11 Aug 2011
First published
19 Aug 2011

Chem. Commun., 2011,47, 10455-10457

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Diffusion of small molecules inside a peptide hydrogel

Y. Feng, M. Lee, M. Taraban and Y. B. Yu, Chem. Commun., 2011, 47, 10455 DOI: 10.1039/C1CC13943F

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