Issue 37, 2011
From the journal:

Chemical Communications

Detection of the Pseudomonas Quinolone Signal (PQS) by cyclic voltammetry and amperometry using a boron doped diamond electrode†

Lin Zhou,ab   Jeremy D. Glennon,ab   John H. T. Luong,c   F. Jerry Reen,d   Fergal O'Gara,d   Christina McSweeneyb  and  Gerard P. McGlacken*b  

* Corresponding authors

a Innovative chromatography Group, Irish Separation Science Cluster (ISSC), University College Cork, Ireland

b Department of Chemistry and Analytical and Biological Research Facility, University College Cork, Ireland
E-mail: g.mcglacken@ucc.ie
Fax: +353 (0)214902866

c National Research Council Canada, Biotechnology Research Institute, Montreal, Quebec, Canada

d BIOMERIT Research Centre, Department of Microbiology, University College Cork, Ireland

Abstract

2-Heptyl-3-hydroxy-4-quinolone, known as the Pseudomonas Quinolone Signal, is a key regulator of bacterial cooperative behaviour known as quorum sensing. A simple electrochemical strategy was employed for its sensitive detection using a bare boron-doped diamond electrode by cyclic voltammetry and amperometry. PQS (and potentially other quinolones) was then detected in cultures of P. aeruginosa pqsL− mutant strains.

Graphical abstract: Detection of the Pseudomonas Quinolone Signal (PQS) by cyclic voltammetry and amperometry using a boron doped diamond electrode

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Article information

DOI
https://doi.org/10.1039/C1CC13997E
Article type
Communication
Submitted
04 Jul 2011
Accepted
10 Aug 2011
First published
19 Aug 2011

Chem. Commun., 2011,47, 10347-10349

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Detection of the Pseudomonas Quinolone Signal (PQS) by cyclic voltammetry and amperometry using a boron doped diamond electrode

L. Zhou, J. D. Glennon, J. H. T. Luong, F. J. Reen, F. O'Gara, C. McSweeney and G. P. McGlacken, Chem. Commun., 2011, 47, 10347 DOI: 10.1039/C1CC13997E

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