Issue 6, 2011

Lewis acid-catalysed one pot synthesis of substituted xanthenes

Abstract

A direct synthesis of substituted xanthenes from salicylaldehydes and cyclohexenones or tetralones has been developed. The reaction is catalysed by Lewis acids like scandium triflate and furnishes substituted xanthenes in good to excellent yields using either microwave or thermal heating. Microwave heating results in significantly shortened reaction times of 30 min and generally higher yields.

Graphical abstract: Lewis acid-catalysed one pot synthesis of substituted xanthenes

Supplementary files

Article information

Article type
Paper
Submitted
29 Oct 2010
Accepted
15 Dec 2010
First published
15 Dec 2010

Org. Biomol. Chem., 2011,9, 1744-1748

Lewis acid-catalysed one pot synthesis of substituted xanthenes

E. Böβ, T. Hillringhaus, J. Nitsch and M. Klussmann, Org. Biomol. Chem., 2011, 9, 1744 DOI: 10.1039/C0OB00954G

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