Issue 9, 2011
From the journal:

Organic & Biomolecular Chemistry

Synthetic studies towards marmycins A and B: development of the vinylogous aldol–aza-Michael domino reaction†

Emmanuel Bourcet,a   Manuel C. Bröhmer,a   Martin Niegerb  and  Stefan Bräse*a  

* Corresponding authors

a Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, Karlsruhe, Germany
E-mail: braese@kit.edu
Fax: + 49 721 608 4 8581
Tel: + 49 721 608 4 2902

b Laboratory of Inorganic Chemistry, University of Helsinki, Helsinki, Finland

Abstract

The vinylogous aldol–aza-Michael domino reaction between 2-aminobenzaldehydes and prenal was developed to build up the core of natural products marmycin A and B without the need of protective groups.

Graphical abstract: Synthetic studies towards marmycins A and B: development of the vinylogous aldol–aza-Michael domino reaction

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Article information

DOI
https://doi.org/10.1039/C1OB05124E
Article type
Communication
Submitted
22 Jan 2011
Accepted
15 Feb 2011
First published
16 Feb 2011

Org. Biomol. Chem., 2011,9, 3136-3138

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Synthetic studies towards marmycins A and B: development of the vinylogous aldol–aza-Michael domino reaction

E. Bourcet, M. C. Bröhmer, M. Nieger and S. Bräse, Org. Biomol. Chem., 2011, 9, 3136 DOI: 10.1039/C1OB05124E

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