Anti-virulence Strategy against Brucella suis: Synthesis, Biological Evaluation and Molecular Modeling of Selective Histidinol Dehydrogenase Inhibitors
Abstract
In the facultative intracellular pathogen Brucella suis,
* Corresponding authors
a
Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS-Université Montpellier I-Université Montpellier II, Ecole Nationale Supérieure de Chimie de Montpellier, 8 rue de l'Ecole Normale, Montpellier Cedex, France
E-mail:
jean-yves.winum@univ-montp2.fr
Tel: +33-467147234
b
Centre d’études d'agents Pathogènes et Biotechnologie pour la Santé (CPBS), UMR 5236 CNRS-Université Montpellier I-Université Montpellier II, 1919 Route de Mende, Montpellier Cedex 5, France
E-mail:
Stephan.Kohler@cpbs.cnrs.fr
c Drug Design & Discovery Center, Department of Pharmacy, University of Namur (FUNDP), Belgium
In the facultative intracellular pathogen Brucella suis,
M. Abdo, P. Joseph, J. Mortier, F. Turtaut, J. Montero, B. Masereel, S. Köhler and J. Winum, Org. Biomol. Chem., 2011, 9, 3681 DOI: 10.1039/C1OB05149K
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