Exploiting a novel size exclusion phenomenon for enantioselective acid/base cascade catalysis†
Abstract
A novel size exclusion phenomenon between PS-BEMP and sterically bulky BPAs, has been discovered and exploited in a one-pot base-catalysed
* Corresponding authors
a
Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK
E-mail:
Darren.dixon@chem.ox.ac.uk
Fax: +44 (0)1865 285002
Tel: +44 (0)1865 275648
b School of Chemistry, The University of Manchester, Oxford Road, Manchester M13 9PL, UK
c Pfizer Neusentis, The Portway Building, Granta Park, Cambridge, UK
A novel size exclusion phenomenon between PS-BEMP and sterically bulky BPAs, has been discovered and exploited in a one-pot base-catalysed
M. E. Muratore, L. Shi<small xmlns="http://www.rsc.org/schema/rscart38"> <sup /> </small>, A. W. Pilling, R. I. Storer and D. J. Dixon, Chem. Commun., 2012, 48, 6351 DOI: 10.1039/C2CC32258G
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