Issue 35, 2012
From the journal:

Dalton Transactions

A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM)†

Jonathan S. Ward,a   Jason M. Lynam,*a   James W. B. Moir,b   David E. Sanin,b   Adrian P. Mountfordb  and  Ian J. S. Fairlamb*a  

* Corresponding authors

a Department of Chemistry, University of York, Heslington, York, UK
E-mail: jason.lynam@york.ac.uk, ian.fairlamb@york.ac.uk
Fax: +44 (0)1904 322516
Tel: +44 (0)1904 324091

b Centre for Immunology and Infection, Department of Biology, University of York, Heslington, York, UK

Abstract

A new class of photochemically-activated CO-releasing molecule (photo-CO-RM), based on a Mn(CO)4(C^N) system, is reported in this study. Three CO molecules are released per CO-RM molecule. Complex 3 is a fast releaser, thermally stable in the dark and a viable therapeutic agent.

Graphical abstract: A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM)

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2DT31588B
Article type
Communication
Submitted
17 Jul 2012
Accepted
18 Jul 2012
First published
31 Jul 2012

Dalton Trans., 2012,41, 10514-10517

Permissions

Request permissions

A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM)

J. S. Ward, J. M. Lynam, J. W. B. Moir, D. E. Sanin, A. P. Mountford and I. J. S. Fairlamb, Dalton Trans., 2012, 41, 10514 DOI: 10.1039/C2DT31588B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements