We demonstrate the synthesis and immobilization of natural product hybrids featuring an acyl-homoserine lactone and a nitrodopamine onto biocompatible TiO2 surfaces through an operationally simple dip-and-rinse procedure. The resulting immobilized hybrids were shown to be powerful quorum sensing (QS) activators in Pseudomonas strains acting by slow release from the surface.
J. Gomes, A. Grunau, A. K. Lawrence, L. Eberl and K. Gademann, Chem. Commun., 2013, 49, 155 DOI: 10.1039/C2CC37287H
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