Issue 53, 2013
From the journal:

Chemical Communications

A click-activated fluorescent probe for selective detection of hydrazoic acid and its application in biological imaging†

Yi Zhou,a   Yue-Wei Yao,ab   Qi Qi,b   Yuan Fang,a   Jing-Yun Lic  and  Cheng Yao*a  

* Corresponding authors

a State Key Laboratory of Materials-Oriented Chemical Engineering and College of Science, Nanjing University of Technology, Nanjing 210009, P. R. China
E-mail: yaochengnjut@126.com
Fax: +86-25-8358-7433

b College of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China

c Model Animal Research Center, Nanjing University, Nanjing 210061, P. R. China

Abstract

Here we present a new approach to aqueous hydrazoic acid detection through the synthesis and evaluation of an alkyne-based fluorescent probe, which could be applied in the monitoring of hydrazoic acid in both living Hela cells and larval zebrafish. This probe can also serve as an early warning automaton which would alert when both azide and protons exist over the threshold value.

Graphical abstract: A click-activated fluorescent probe for selective detection of hydrazoic acid and its application in biological imaging

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC40698A
Article type
Communication
Submitted
27 Jan 2013
Accepted
09 Mar 2013
First published
13 Mar 2013

Chem. Commun., 2013,49, 5924-5926

Permissions

Request permissions

A click-activated fluorescent probe for selective detection of hydrazoic acid and its application in biological imaging

Y. Zhou, Y. Yao, Q. Qi, Y. Fang, J. Li and C. Yao, Chem. Commun., 2013, 49, 5924 DOI: 10.1039/C3CC40698A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements