Issue 42, 2013
From the journal:

Chemical Communications

Biomolecular release triggered by glucose input – bioelectronic coupling of sensing and actuating systems†

Shay Mailloux,a   Jan Halámek,*a   Lenka Halámková,ab   Alexander Tokarev,a   Sergiy Minkoa  and  Evgeny Katz*a  

* Corresponding authors

a Department of Chemistry and Biomolecular Science, Clarkson University, Potsdam, NY 13699, USA
E-mail: ekatz@clarkson.edu, jhalamek@clarkson.edu
Fax: +1-315-268-6610
Tel: +1-315-268-4421

b Department of Biology, Clarkson University, Potsdam, NY 13699, USA

Abstract

A drug-mimicking release process was triggered by a glucose signal resulting in the formation of a negative potential on an electrode modified with PQQ-dependent glucose dehydrogenase. This electrode was coupled with another electrode coated with an Fe+3-crosslinked alginate polymer film, which was dissolved upon formation of the negative potential releasing entrapped species.

Graphical abstract: Biomolecular release triggered by glucose input – bioelectronic coupling of sensing and actuating systems

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Article information

DOI
https://doi.org/10.1039/C3CC42027B
Article type
Communication
Submitted
20 Mar 2013
Accepted
08 Apr 2013
First published
09 Apr 2013

Chem. Commun., 2013,49, 4755-4757

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Biomolecular release triggered by glucose input – bioelectronic coupling of sensing and actuating systems

S. Mailloux, J. Halámek, L. Halámková, A. Tokarev, S. Minko and E. Katz, Chem. Commun., 2013, 49, 4755 DOI: 10.1039/C3CC42027B

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