Issue 99, 2013
From the journal:

Chemical Communications

A new versatile approach to synthesise enantioenriched 3-hydroxyoxindoles, 1,3-dihydroisobenzofuran and 3-isochromanone derivatives by a rhodium-catalyzed asymmetric arylation–cyclization sequence†

Yi Li,a   Dong-Xing Zhua  and  Ming-Hua Xu*a  

* Corresponding authors

a State key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China
E-mail: xumh@simm.ac.cn
Fax: +86 21-50807388

Abstract

A novel arylation–cyclization strategy for the highly enantioselective synthesis of titled heterocycles with a quaternary stereogenic center has been developed.

Graphical abstract: A new versatile approach to synthesise enantioenriched 3-hydroxyoxindoles, 1,3-dihydroisobenzofuran and 3-isochromanone derivatives by a rhodium-catalyzed asymmetric arylation–cyclization sequence

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Article information

DOI
https://doi.org/10.1039/C3CC47927G
Article type
Communication
Submitted
15 Oct 2013
Accepted
19 Oct 2013
First published
22 Oct 2013

Chem. Commun., 2013,49, 11659-11661

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A new versatile approach to synthesise enantioenriched 3-hydroxyoxindoles, 1,3-dihydroisobenzofuran and 3-isochromanone derivatives by a rhodium-catalyzed asymmetric arylation–cyclization sequence

Y. Li, D. Zhu and M. Xu, Chem. Commun., 2013, 49, 11659 DOI: 10.1039/C3CC47927G

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