Issue 29, 2014
From the journal:

Chemical Communications

Multiplex detection of nucleic acids using a low cost microfluidic chip and a personal glucose meter at the point-of-care†

Qing Wang,a   Hui Wang,a   Xiaohai Yang,a   Kemin Wang,*a   Fang Liu,a   Qing Zhao,a   Pei Liua  and  Rongjuan Liua  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China
E-mail: kmwang@hnu.edu.cn
Fax: +86 731 88821566
Tel: +86 731 88821566

Abstract

A simple assay for multiplex DNA detection has been developed using a microfluidic chip and a personal glucose meter. By using this system, multiplex detection of three genotypes of hepatitis B virus DNA was possible with a detection limit of 10 pM. This point-of-care assay represented a versatile platform for sensitive multiplex target detection.

Graphical abstract: Multiplex detection of nucleic acids using a low cost microfluidic chip and a personal glucose meter at the point-of-care

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Article information

DOI
https://doi.org/10.1039/C4CC00133H
Article type
Communication
Submitted
07 Jan 2014
Accepted
17 Feb 2014
First published
17 Feb 2014

Chem. Commun., 2014,50, 3824-3826

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Multiplex detection of nucleic acids using a low cost microfluidic chip and a personal glucose meter at the point-of-care

Q. Wang, H. Wang, X. Yang, K. Wang, F. Liu, Q. Zhao, P. Liu and R. Liu, Chem. Commun., 2014, 50, 3824 DOI: 10.1039/C4CC00133H

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