Issue 61, 2014

A fluorescent light-up probe with AIE characteristics for specific mitochondrial imaging to identify differentiating brown adipose cells

Abstract

We report the design and synthesis of a specific mitochondrial fluorescent probe AIE-MitoGreen-1 with AIE characteristics to monitor the mitochondrial morphology changes and identify the differentiation process of living brown adipose cells. The probe AIE-MitoGreen-1 has significant advantages such as high cell-permeability, good mitochondrial retention, low background fluorescence, large Stokes shift, and low toxicity.

Graphical abstract: A fluorescent light-up probe with AIE characteristics for specific mitochondrial imaging to identify differentiating brown adipose cells

Supplementary files

Article information

Article type
Communication
Submitted
19 Jan 2014
Accepted
09 Jun 2014
First published
09 Jun 2014

Chem. Commun., 2014,50, 8312-8315

Author version available

A fluorescent light-up probe with AIE characteristics for specific mitochondrial imaging to identify differentiating brown adipose cells

M. Gao, C. K. Sim, C. W. T. Leung, Q. Hu, G. Feng, F. Xu, B. Z. Tang and B. Liu, Chem. Commun., 2014, 50, 8312 DOI: 10.1039/C4CC00452C

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