Two promising uncharged reactivators for inhibited human BChE and AChE have been described. These compounds show an ability to reactivate VX-inhibited BChE largely superior to those of known pyridinium aldoximes. Moreover, these oximes also exhibit a good ability to reactivate VX-, tabun- and paraoxon-inhibited human AChE.
J. Renou, M. Loiodice, M. Arboléas, R. Baati, L. Jean, F. Nachon and P. Renard, Chem. Commun., 2014, 50, 3947 DOI: 10.1039/C4CC00561A
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