The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of the polymer within HeLa cells were investigated.
L. Zhang, F. Su, S. Buizer, X. Kong, F. Lee, K. Day, Y. Tian and D. R. Meldrum, Chem. Commun., 2014, 50, 6920 DOI: 10.1039/C4CC01110D
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