Manganese porphyrin–double stranded DNA complex guided in situ deposition of polyaniline for electrochemical thrombin detection†
Abstract
In this work, we proposed a novel electrochemical strategy for sensitive detection of thrombin (TB) based on in situ generation of polyaniline (PANI) as a redox mediator by using a manganese porphyrin–double stranded DNA (MnTMPyP–dsDNA) peroxidase-like artificial enzyme mimic as a powerful catalyst and template.