Issue 78, 2014
From the journal:

Chemical Communications

A selective and sensitive fluorescent albumin probe for the determination of urinary albumin†

Ying-Yi Wu,a   Wan-Ting Yu,a   Tai-Cheng Hou,a   Tao-Kai Liu,a   Chi-Ling Huang,a   I-Chia Chenab  and  Kui-Thong Tan*ab  

* Corresponding authors

a Department of Chemistry, National Tsing Hua University, 101 Sec. 2, Kuang Fu Rd, Hsinchu 30013, Taiwan, Republic of China
E-mail: kttan@mx.nthu.edu.tw

b Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, 101 Sec. 2, Kuang Fu Rd, Hsinchu 30013, Taiwan, Republic of China

Abstract

In this communication, we report a simple albumin probe based on a fluorescent molecular rotor for the detection of trace albumin levels in urine. In the presence of albumin, the probe exhibits remarkable 400-fold fluorescence enhancement with high selectivity and sensitivity. The probe was successfully applied in the quantitative detection of urinary albumin.

Graphical abstract: A selective and sensitive fluorescent albumin probe for the determination of urinary albumin

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4CC04236K
Article type
Communication
Submitted
03 Jun 2014
Accepted
05 Aug 2014
First published
08 Aug 2014

Chem. Commun., 2014,50, 11507-11510

Permissions

Request permissions

A selective and sensitive fluorescent albumin probe for the determination of urinary albumin

Y. Wu, W. Yu, T. Hou, T. Liu, C. Huang, I. Chen and K. Tan, Chem. Commun., 2014, 50, 11507 DOI: 10.1039/C4CC04236K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements